Landslides are triggered by earthquakes, volcanoes, floods, and heavy continuous rainfall. For most types of slope failure, soil moisture plays a critical role because increased pore water pressure reduces the soil strength and increases stress. However, in-situ soil moisture profiles are rarely measured. To establish the soil moisture and landslide relationship, a qualitative comparison among soil moisture derived from AMSR-E, precipitation from TRMM and major landslide events was conducted. This study shows that it is possible to estimate antecedent soil moisture conditions using AMSR-E and TRMM satellite data in landslide prone areas. AMSR-E data show distinct annual patterns of soil moisture that reflect observed rainfall patterns from TRMM. Results also show enhanced AMSR-E soil moisture and TRMM rainfall prior to major landslide events in landslide prone regions of California, U.S.; Leyte, Philippines; and Dhading, Nepal.